Mary Armanios, M.D.

Phone: (410) 955-8964

Fax: (410) 614-2987

Interests:

• pulmonary diseases
• Telomerase

Titles

Assistant Professor of Oncology

Schools/Degrees

M.D., Ohio State University College of Medicine

Training

Internal Medicine Internship, Ohio State University, Columbus, OH

Combined Internal Medicine and Pediatrics Residency, Ohio State University

Medical Oncology Fellowship, Johns Hopkins University School of Medicine and Kimmel Cancer Center, Baltimore, MD

Certifications

Internal Medicine, Pediatrics, Medical Oncology

Clinical Interests

Thoracic Oncology

Dr. Mary Armanios is an Assistant Professor in the Department of Oncology at the Johns Hopkins School of Medicine in Baltimore.  She earned her medical degree at the Ohio State University and went on to complete a combined internal medicine and pediatrics residency.  She joined the Johns Hopkins medical oncology fellowship program in 2001. During her post-doctoral training, Dr. Armanios developed an interest in the genetics of inherited syndromes of telomere shortening.  She has been on the Johns Hopkins faculty since 2005 and her current research aims to bridge basic knowledge of telomere biology to clinically relevant paradigms. 

Journal Citations

1. Gimm O, Armanios M, Dziema H, Neuman HPH, Eng C. Somatic and occultgerm-line mutations in SDHD, a mitochondrial complex II gene, in nonfamilialpheochromocytoma. Cancer Research 2000;60:6822-6825.

2. Qi L, Strong MA, Karim BO, Armanios M, Huso DL, Greider CW. Short telomeresand loss of Atm cooperatively increase telomere dysfunction and suppresstumorigenesis, Cancer Research 2003;63:8188-96.

3. Armanios M, Grossman SA, Yang S, White B, Orens J. Transmission ofglioblastoma multiforme after bilateral lung transplantation, Neuro-oncology2004;6259-63.

4. Armanios M, Xu R, Forastiere A, Haller D, Kugler J, Benson AB. AdjuvantChemotherapy for Resected Adenocarcinoma of the Esophagus, Gastroesophageal(GE) Junction and Cardia (E8296): A Phase II Trial of the EasternCooperative Oncology Group, Journal of Clinical Oncology 2004;22:4495-9.

5. Armanios M, Chen JL, Chang Y-P, Brodsky RA, Hawkins A, Griffin CA, EshlemanJR, Cohen AR, Chakravarti A, Hamosh A, Greider CW. Haploinsufficiency ofTelomerase Reverse Transcriptase Leads to Anticipation in Autosomal DominantDyskeratosis Congenita, Proceedings of the National Academy of Sciences 2005102(44):15960-4.

6. Hao L-Y, Armanios M, Strong MA, Karim B, Feldser DM, Huso D, Greider CW.Short Telomeres, Even in the Presence of Telomerase, Limit Tissue RenewalCapacity, Cell 2005 123:1121-31.

7. Armanios M and Greider CW. Telomerase and Cancer Stem Cells. Cold SpringHarbor Symposia on Quantitative Biology: Molecular Approaches to ControllingCancer, 2005 70: 205-08.8. Armanios M, Chen JL, Cogan JD, Alder JK, Ingersoll RG, Markin C, Lawson WE,Xie M, Vulto I, Phillips JA, Lansdorp PM, Greider CW, Loyd JE. TelomeraseMutations in Families with Idiopathic Pulmonary Fibrosis, New England Journal ofMedicine, in press.

8.   Armanios MY, Chen JL, Cogan JD, Alder JK, Ingersoll RG, Markin C, Lawson WE, Xie M, Vulto I, Phillips JA, Lansdorp PM, Greider CW, Loyd JE.  Telomerase Mutations in Families with Idiopathic Pulmonary Fibrosis, New England Journal of Medicine, 2007 316: 1317-26.

9.   Alder JK, Chen JL, Lancaster L, Danoff S, Su SC, Cogan JD, Vulto I, Xie M, Qi X,    Tuder, RM, Phillips JA 3rd, Lansdorp PM, Loyd JE, Armanios MY.  Short telomeres in idiopathic pulmonary fibrosis and related disorders, in press PNAS 105(35):13051-6, 2008.